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Cancer Cause and Prevention Research

Program Information

Popular name

Cancer Cause and Prevention Research

Program Number

93.393

Program objective

To identify cancer risks and risk reduction strategies, to identify factors that cause cancer in humans, and to discover and develop mechanisms for cancer prevention and preventive interventions in humans. Research programs include: (1) chemical, physical and molecular carcinogenesis; (2) screening, early detection and risk assessment, including biomarker discovery, development and validation; (3) epidemiology; (4) nutrition and bioactive food components; (5) immunology and vaccines; (6) field studies and statistics; (7) cancer chemoprevention and interception; (8) pre-clinical and clinical agent development; (9) organ site studies and clinical trials; (10) health-related quality of life and patient-centered outcomes; and (11) supportive care and management of symptoms and toxicities. Small Business Innovation Research (SBIR) program: To expand and improve the SBIR program; to stimulate technical innovation; to increase private sector commercialization of innovations derived from Federal research and development funding; to increase small business participation in Federal research and development; and to foster and encourage participation in innovation and entrepreneurship by women and socially/economically disadvantaged persons. Small Business Technology Transfer (STTR) program: To stimulate and foster scientific and technological innovation through cooperative research and development carried out between small business concerns and research institutions; to foster technology transfer through cooperative research and development between small business concerns and research institutions; to increase private sector commercialization of innovations derived from Federal research and development funding, and foster participation in innovation and entrepreneurship by women and socially/economically disadvantaged persons.

Program expenditures, by FY (2023 - 2025)

This chart shows obligations for the program by fiscal year. All data for this chart was provided by the administering agency and sourced from SAM.gov, USASpending.gov, and Treasury.gov.

For more information on each of these data sources, please see the About the data page.

Additional program information

  1. 2016

    FY 2016 RPG est. 645 total awards Competing FY2016 RPG actual 342 awards which were 13.3% of applications received. Competing FY2016 SBIR/STTR actual 13 awards which were 11.4% of applications received.

  2. 2017

    FY2017 estimated total awards to be made is 308

  3. 2018

    FY2018 estimated total awards to be made is 327.

  4. 2019

    FY2019 actual total awards to be made is 306.

  5. 2020

    FY2020 actual total awards made was 292.

  6. 2021

    FY2021 total awards to be made is 294.

  7. 2022

    FY2022 actual awards made was 331.

  8. 2023

    FY2023 actual total awards made was 283.

  9. 2024

    FY2024 estimated total awards to be made is 1,308.

  10. 2025

    FY2025 estimated total awards to be made is 1,449.

Single Audit Applies (2 CFR Part 200 Subpart F):

For additional information on single audit requirements for this program, review the current Compliance Supplement.

OMB is working with the U.S. Government Accountability Office (GAO) and agency offices of inspectors general to include links to relevant oversight reports. This section will be updated once this information is made available.

42 CFR 52; 45 CFR 75; NIH Grants Policy Statement (10/1/16); Grants will be available under the authority of and administered in accordance with the NIH Grants Policy Statement and Federal regulations at 42 CFR 52 and 42 U.S.C. 241; Omnibus Solicitation of the Public Health Service for Small Business Innovation Research (SBIR) Grant and Cooperative Agreement Applications. Omnibus Solicitation of the National Institutes of Health for Small Business Technology Transfer (STTR) Grant Applications.

  1. Public Health Service Act, Sections 301, 410 and 411, Public Law 78-410, as amended, Public Law 100-607, as amended, 42 U.S.C. 241, 42 U.S.C. 285 - 285a-1; Small Business Research and Development Enhancement Act of 1992, as amended, Public Law 102-564, as amended; 15 U.S.C. 638.

Program details

Program types

Eligible beneficiaries

  • Individual/Family
  • Other private institution/organization
  • Other public institution/organization
  • Private nonprofit institution/organization
  • Profit organization
  • Public nonprofit institution/organization
  • Quasi-public nonprofit organization

Additional resources