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The BRAIN Initiative
93.372
To provide extramural research support for the Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative’s aim of revolutionizing our understanding of the brain and its function in unprecedented detail. The NIH BRAIN Initiative’s focus is foundational development of new technologies and tools to map, monitor, and modulate brain circuits in model systems and humans – toward the ultimate goal of treating and curing human brain disorders. BRAIN Initiative research adheres to open, ethical, and inclusive science – and requires diverse expertise across all domains. BRAIN-supported research areas include comprehensive cataloguing, mapping, accessing and characterization of brain cell types ; probing neural circuits that interact and produce behavior, cognition, and emotion; developing and employing new technologies to monitor function and connectivity of synapses, circuits, and whole brains; partnering with human research participants, including utilizing neurotechnologies in first-in-human clinical studies, to study the human brain in the context of brain injury and brain disorders; and establishing data-sharing platforms and computational models that help decode brain processes and functions. Within these scientific focus areas, the Initiative supports research project grants, cooperative agreements, workforce development awards and Small Business Innovation Research awards. Research supported by the Initiative has a strong commitment to broad dissemination of newly developed technologies, and to considering neuroethical issues related to studying the human brain and the neuroscience advances that follow from this research. New frontiers for BRAIN research will adhere to, and build on, what has been learned to date and adapt to the rapidly changing scientific landscape and neuroscience ecosystem.
This chart shows obligations for the program by fiscal year. All data for this chart was provided by the
administering agency and sourced from SAM.gov, USASpending.gov, and Treasury.gov.
For more information on each of these data sources, please see the
About the data page.
N/A
$10,000,000
$86,000,000
NIH BRAIN Initiative-funded researchers (funded from all of these scientific priority areas) have made significant advances – made possible in part by 21st Century Cures funding. They have created a system for studying circuits in a postmortem animal brain; programmed a computer to mimic natural speech from people’s brain signals; and developed a new viral genetic-based brain mapping tool. Through advanced imaging techniques, they have watched neurons fire in the brains of running mice and made high-speed, high-resolution, 3D films of a nervous system in action. These scientists have created the most detailed ‘parts list’ of the human brain to date and shown how it can remarkably adapt after one half is damaged or remove by re-wiring specialized neural networks.
There were 62 competing research application awards made.
There were 18 competing research application awards made.
No expected competing research application awards to be made.
Single Audit Applies (2 CFR Part 200 Subpart F):
For additional information on single audit requirements for this program, review the current Compliance Supplement.
OMB is working with the U.S. Government Accountability Office (GAO) and agency offices of inspectors general to include links to relevant oversight reports. This section will be updated once this information is made available.
